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Spectral Libraries

Why are we reinventing the wheel with every database search??

Spectral libraries offer enormous advantages over traditional database search routines. They are also in short supply and tools to use them are limited..

Additional limitations include: Incomplete libraries, decoy implementation, differences in analytical platforms (ie altered fragmentation patterns based on instrument used).

Proteome Tools - Prosit

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Youtube video
Web server for RAW file analysis

MassIVE-KB Peptide Spectral Libraries

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Step by step - DDA implementation

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Mascot using PD for quant

MetaMorpheus

Using SLs

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Mascot how to page

Metamorpheus how to page (wiki)

and home page

In-house libraries

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hECM

mECM

hPlasma

mPlasma

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